MITOCHONDRIAL REACTIVE OXYGEN SPECIES - Research Front Map

EMERGING RESEARCH FRONTS

Research Front Map - April 2008

This Research Front on MITOCHONDRIAL REACTIVE OXYGEN SPECIES from the field of Biology & Biochemistry was selected for mapping from the list of Emerging Research Fronts for April 2008 (data from the sixth bimonthly period of 2007). The map is a diagrammatic representation of the 13 core papers comprising the front. Each circle represents a highly cited paper whose bibliographic information is displayed when the user clicks on the circle. The lines between circles represent the strongest co-citation links for each paper (that is, indicating that the papers are frequently cited together). Papers close to each other on the map are generally more highly co-cited. The most recent paper(s) are indicated in pink.

MITOCHONDRIAL REACTIVE OXYGEN SPECIES

Core Papers

Label: Echtay-2002
Title: Superoxide activates mitochondrial uncoupling proteins
Journal: NATURE, 415 (6867): 96-99 JAN 3 2002
Citations: 350
Authors: Echtay, KS;Roussel, D;St-Pierre, J;Jekabsons, MB;Cadenas, S;Stuart, JA;Harper, JA;Roebuck, SJ;Morrison, A;Pickering, S;Clapham, JC;Brand, MD
Addresses:
MRC, Dunn Human Nutr Unit, Hills Rd, Cambridge CB2 2XY, England
MRC, Dunn Human Nutr Unit, Cambridge CB2 2XY, England
GlaxoSmithKline, Dept Comparat Genome, Harlow CM19 5AW, Essex, England
GlaxoSmithKline, Dept Vasc Biol, Harlow CM19 5AW, Essex, England

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Label: Turrens-2003
Title: Mitochondrial formation of reactive oxygen species
Journal: J PHYSIOL-LONDON, 552 (2): 335-344 OCT 15 2003
Citations: 249
Authors: Turrens, JF
Addresses:
Univ S Alabama, Dept Biomed Sci, UCOM 6000, Mobile, AL 36688 USA
Univ S Alabama, Dept Biomed Sci, Mobile, AL 36688 USA

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Label: Liu-2002
Title: Generation of reactive oxygen species by the mitochondrial electron transport chain
Journal: J NEUROCHEM, 80 (5): 780-787 MAR 2002
Citations: 210
Authors: Liu, YB;Fiskum, G;Schubert, D
Addresses:
Salk Inst Biol Studies, Cellular Neurobiol Lab, 10010 N Torrey Pines Rd, La Jolla, CA 92037 USA
Salk Inst Biol Studies, Cellular Neurobiol Lab, La Jolla, CA 92037 USA
Univ Maryland, Sch Med, Dept Anesthesiol, Baltimore, MD 21201 USA

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Label: St-Pierre-2002
Title: Topology of superoxide production from different sites in the mitochondrial electron transport chain
Journal: J BIOL CHEM, 277 (47): 44784-44790 NOV 22 2002
Citations: 210
Authors: St-Pierre, J;Buckingham, JA;Roebuck, SJ;Brand, MD
Addresses:
Dana Farber Canc Inst, SM 958, Boston, MA 02115 USA
MRC Dunn Human Nutr Unit, Cambridge CB2 2XY, England

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Label: Chen-2003
Title: Production of reactive oxygen species by mitochondria - Central role of complex III
Journal: J BIOL CHEM, 278 (38): 36027-36031 SEP 19 2003
Citations: 189
Authors: Chen, Q;Vazquez, EJ;Moghaddas, S;Hoppel, CL;Lesnefsky, EJ
Addresses:
Louis Stokes Vet Affairs Med Ctr, Med Serv 111W, Cardiol Sect, 10701 E Blvd, Cleveland, OH 44106 USA
Case Western Reserve Univ, Dept Med, Div Cardiol, Cleveland, OH 44106 USA
Case Western Reserve Univ, Dept Med, Div Clin Pharmacol, Cleveland, OH 44106 USA
Case Western Reserve Univ, Dept Med, Div Pharmacol, Cleveland, OH 44106 USA
Louis Stokes Vet Affairs Med Ctr, Ctr Geriatr Res Educ & Clin, Cleveland, OH 44106 USA
Louis Stokes Vet Affairs Med Ctr, Med Serv, Cleveland, OH 44106 USA
Xuzhou Med Coll, Dept Anesthesiol, Xuzhou, Peoples R China

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Label: Brand-2004
Title: Mitochondrial superoxide: Production, biological effects, and activation of uncoupling proteins
Journal: FREE RADICAL BIOL MED, 37 (6): 755-767 SEP 15 2004
Citations: 148
Authors: Brand, MD;Affourtit, C;Esteves, TC;Green, K;Lambert, AJ;Miwa, S;Pakay, JL;Parker, N
Addresses:
MRC, Dunn Human Nutr Unit, Hills Rd, Cambridge CB2 2XY, England
MRC, Dunn Human Nutr Unit, Cambridge CB2 2XY, England

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Label: Li-2003
Title: Mitochondrial complex I inhibitor rotenone induces apoptosis through enhancing mitochondrial reactive oxygen species production
Journal: J BIOL CHEM, 278 (10): 8516-8525 MAR 7 2003
Citations: 139
Authors: Li, NY;Ragheb, K;Lawler, G;Sturgist, J;Rajwa, B;Melendez, JA;Robinson, JP
Addresses:
Purdue Univ, Cytometry Labs, Dept Basic Med Sci, W Lafayette, IN 47907 USA
Purdue Univ, Cytometry Labs, Dept Basic Med Sci, W Lafayette, IN 47907 USA
Albany Med Coll, Ctr Immunol & Microbial Dis, Albany, NY 12208 USA

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Label: Kushnareva-2002
Title: Complex I-mediated reactive oxygen species generation: modulation by cytochrome c and NAD(P)(+) oxidation-reduction state
Journal: BIOCHEM J, 368: 545-553 Part 2 DEC 1 2002
Citations: 128
Authors: Kushnareva, Y;Murphy, AN;Andreyev, A
Addresses:
Mitochondrial Biol MitoKor, 11494 Sorrento Valley Rd, San Diego, CA 92024 USA
Mitochondrial Biol MitoKor, San Diego, CA 92024 USA

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Label: Mattiasson-2003
Title: Uncoupling protein-2 prevents neuronal death and diminishes brain dysfunction after stroke and brain trauma
Journal: NATURE MED, 9 (8): 1062-1068 AUG 2003
Citations: 125
Authors: Mattiasson, G;Shamloo, M;Gido, G;Mathi, K;Tomasevic, G;Yi, SL;Warden, CH;Castilho, RF;Melcher, T;Gonzalez-Zulueta, M;Nikolich, K;Wieloch, T
Addresses:
Wallenberg Neurosci Ctr, BMC A13, S-22184 Lund, Sweden
Wallenberg Neurosci Ctr, S-22184 Lund, Sweden
AGY Therapeut Inc, San Francisco, CA 94080 USA
Univ Calif Davis, Sch Med, Div Biol Sci, Neurobiol Sect, Davis, CA 95616 USA
State Univ Campinas, Sch Med Sci, Dept Clin Pathol, BR-13083970 Campinas, SP, Brazil

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Label: Echtay-2002
Title: Superoxide activates mitochondrial uncoupling protein 2 from the matrix side - Studies using targeted antioxidants
Journal: J BIOL CHEM, 277 (49): 47129-47135 DEC 6 2002
Citations: 122
Authors: Echtay, KS;Murphy, MP;Smith, RAJ;Talbot, DA;Brand, MD
Addresses:
MRC, Dunn Human Nutr Unit, Hills Rd, Cambridge CB2 2XY, England
MRC, Dunn Human Nutr Unit, Cambridge CB2 2XY, England
Univ Otago, Dept Chem, Dunedin, New Zealand

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Label: Krauss-2003
Title: Superoxide-mediated activation of uncoupling protein 2 causes pancreatic beta cell dysfunction
Journal: J CLIN INVEST, 112 (12): 1831-1842 DEC 2003
Citations: 91
Authors: Krauss, S;Zhang, CY;Scorrano, L;Dalgaard, LT;St-Pierre, J;Grey, ST;Lowell, BB
Addresses:
Beth Israel Deaconess Med Ctr, Div Endocrinol, Res N RN-325,99 Brookline Ave, Boston, MA 02215 USA
Beth Israel Deaconess Med Ctr, Div Endocrinol, Boston, MA 02215 USA
Harvard Univ, Sch Med, Boston, MA USA
Harvard Univ, Sch Med, Dept Canc Immunol & AIDS, Boston, MA USA
Harvard Univ, Sch Med, Dept Canc Biol, Dana Farber Canc Inst, Boston, MA USA
Harvard Univ, Beth Israel Deaconess Med Ctr, Dept Surg, Boston, MA USA

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Label: Kudin-2004
Title: Characterization of superoxide-producing sites in isolated brain mitochondria
Journal: J BIOL CHEM, 279 (6): 4127-4135 FEB 6 2004
Citations: 79
Authors: Kudin, AP;Bimpong-Buta, NYB;Vielhaber, S;Elger, CE;Kunz, WS
Addresses:
Univ Bonn, Med Ctr, Dept Epileptol, Sigmund Freud Str 25, D-53105 Bonn, Germany
Univ Bonn, Med Ctr, Dept Epileptol, D-53105 Bonn, Germany
Univ Magdeburg, Med Ctr, Dept Neurol, D-39120 Magdeburg, Germany

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Label: Brand-2005
Title: The basal proton conductance of mitochondria depends on adenine nucleotide translocase content
Journal: BIOCHEM J, 392: 353-362 Part 2 DEC 1 2005
Citations: 24
Authors: Brand, MD;Pakay, JL;Ocloo, A;Kokoszka, J;Wallace, DC;Brookes, PS;Cornwall, EJ
Addresses:
MRC, Dunn Human Nutr Unit, Hills Rd, Cambridge CB2 2XY, England
MRC, Dunn Human Nutr Unit, Cambridge CB2 2XY, England
Emory Univ, Sch Publ Hlth, Ctr Mitochondrial Med, Atlanta, GA 30322 USA
Univ Birmingham, Dept Mol & Cellular Pathol, Birmingham, AL 35294 USA

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